This third edition of the classic "how-to" guide incorporates recent changes in policies and procedures of the NIH, with particular emphasis on the role of the Internet in the research proposal process. Completely revised and updated, it reveals the secrets of success used by seasoned investigators, and directs the reader through the maze of NIH bureaucracies. In addition to providing a detailed overview of the entire review process, the book also includes hundreds of tips on how to enhance proposals, excerpts from real proposals, and extensive Internet references. This book is essential to all scientists involved in the grant writing process.

• Considers the reviewer's perspective
• Detailed presentation of the review process
• All sections of the R01 proposal are reviewed
• Hundreds of tips to enhance proposals
• Includes the many recent changes in NIH policies
• Includes many excerpts from real proposals
• Provides extensive Internet references

Part One: Basic Grantsmanship
The NIH and Other Sources of Research Support.
A Strong Proposal.
Proposal Review.
The R01 Research Grant.
The Abstract and Specific Aims.
Background and Significance.
Preliminary Studies.
Research Design and Methods.
The Budget.
Biographical Sketch, and Other Research Support.
Human Subjects.
Animal Subjects.
Consortiums and Contracts, Consultants, Collaborators.
Literature Cited and Appendices.
Revision of an Unfunded Proposal.
Competing Renewal of R01 Proposals (Progress Reports).
Proposal Submission and Supplementary Materials.
Your First Grant Award (R, F, or K).
Advice for Beginners in Academia.

Part Two: Advanced Grantsmanship
Small Business Grants.
Program Project Grants.
Center Grants.
Construction Grants.
T-32 Institutional Research Training Program Grants.
Instrumentation Grants.

Appendix

A: Information Sources: Private Foundation and Government Websites; Study Sections.
B: Summary Statements, Reviewer Comments, Assignment, Award and Triage Letters.
C: Examples of Figures from Preliminary Data.
D: Examples of Design Format.
E: Instructions to Reviewers Concerning Human Subjects.
F: References and Suggested Reading.

This third edition of the classic "how-to" guide incorporates recent changes in policies and procedures of the National Institutes of Health (NIH), with particular emphasis on the role of the Internet in the research proposal process. Completely revised and updated, it reveals the secrets of success used by seasoned investigators, and directs the reader through the maze of NIH bureaucracies. In addition to providing a detailed overview of the entire review process, the book also includes hundreds of tips on how to enhance proposals, excerpts from real proposals, and extensive Internet references. This book is essential to all scientists involved in the grant writing process. Key Features

• Considers the reviewer's expectations in all grant writing advise
• Explains the review process and each section of the NIH R01 proposal in detail
• Improves priority scores with numerous tips on how to develop proposals
• Reveals strategies utilized by veteran proposal writers
• Details recent NIH policy changes, emphasizing Internet use