Plumb’s^™ VETERINARY DRUG HANDBOOK

Find drug dosages and other critical information for prescribing drugs to animals quickly and efficiently in this fully updated new edition of this must-have veterinary resource

The Tenth Edition of Plumb’s^® Veterinary Drug Handbook updates the most comprehensive, detailed, and trusted source of drug information relevant to veterinary medicine. Covering dosages, drug interactions, adverse effects, and contraindications, among other key drug details, this bestselling book is a must for practicing veterinarians and anyone requiring reliable information on the use of drugs in animals. Designed for ease of use, the book surveys an exhaustive list of drugs with applications for a wide variety of species, including dogs, cats, birds, small mammals, and farm animals.

This edition includes updates to all 738 drug monographs and adds 30 new monographs, including 9 new insulin monographs, to its exhaustive coverage of drugs used in the care of animals. This new edition:

• Provides an extensively reviewed and updated version of the must-have veterinary drug reference
• Includes 30 new drug monographs, including 9 new insulin monographs
• Updates all 738 drug monographs, with robust citing of new information
• Covers a wide variety of species, including dogs, cats, birds, small mammals, and farm animals
• Presents detailed dosing information for an exhaustive list of drugs used in animals

Plumb’s^® exhaustive coverage of drugs relevant to the veterinary field makes this book an essential reference for veterinarians, veterinary technicians, veterinary pharmacologists, pharmacists with veterinary patients, and libraries that serve these groups.

Systemic Monographs

Acarbose 1

Acepromazine 2

Acetaminophen 7

Acetazolamide 9

Acetic Acid 11

Acetylcysteine 12

Acyclovir 14

Afoxolaner 16

Aglepristone 18

Albendazole 20

Albumin, Human 22

Albuterol 24

Alendronate 27

Alfaxalone 29

Alfentanil 35

Allopurinol 37

Alprazolam 39

Altrenogest 41

Aluminum Hydroxide 44

Amantadine 45

Amikacin, Systemic 47

Aminocaproic Acid 51

Aminophylline 53

Amiodarone 56

Amitriptyline 58

Amlodipine 62

Ammonium Chloride 65

Amoxicillin 67

Amoxicillin/Clavulanate 70

Amphotericin B 74

Ampicillin 78

Ampicillin/Sulbactam 82

Amprolium 84

Antivenom, Latrodectus mactans 86

Antivenom, Crotalidae 87

Antivenom, North American Coral Snake 90

Apomorphine 92

Apramycin 94

Ascorbic Acid 96

Asparaginase 98

Aspirin 100

Atenolol 103

Atipamezole 106

Atovaquone 108

Atracurium 109

Atropine 112

Auranofin 116

Azathioprine 118

Azithromycin 120

Benazepril 123

Betamethasone (Systemic) 127

Bethanechol 130

Bisacodyl 132

Bismuth Subsalicylate 133

Bleomycin 135

Bromides 137

Bromocriptine 140

Budesonide 142

Bupivacaine 144

Bupivacaine Liposome 147

Buprenorphine 150

Buspirone 155

Butorphanol 157

Butylscopolamine 164

Cabergoline 165

Caffeine 167

Calcitonin 169

Calcitriol 170

Calcium Acetate 172

Calcium, IV (-Borogluconate, -Chloride, -Gluconate) 174

Calcium, Oral (-Carbonate, -Gluconate, -Lactate) 177

Cannabidiol (CBD) 179

Capromorelin 182

Carbimazole 184

Carboplatin 186

Carnitine 189

Carprofen 190

Carvedilol 193

Caspofungin 195

Cefaclor 197

Cefadroxil 198

Cefazolin 201

Cefepime 203

Cefixime 205

Cefotaxime 206

Cefotetan 208

Cefovecin 210

Cefoxitin 212

Cefpodoxime 214

Cefquinome 216

Ceftazidime 219

Ceftiofur Crystalline Free Acid 221

Ceftiofur HCl 224

Ceftiofur Sodium 227

Ceftriaxone 230

Cefuroxime 232

Cephalexin 234

Cephapirin 237

Cetirizine 238

Charcoal, Activated 240

Chlorambucil 243

Chloramphenicol 245

Chlorothiazide 249

Chlorpheniramine 251

Chlorpromazine 253

Chlortetracycline 255

Cholestyramine 257

Chorionic Gonadotropin 259

Ciclesonide 261

Cimetidine 263

Ciprofloxacin 265

Cisapride 269

Cisplatin 271

Citrate, Potassium 274

Clarithromycin 276

Clemastine 279

Clenbuterol 280

Clindamycin 282

Clodronate 286

Clofazimine 288

Clomipramine 289

Clonazepam 292

Clonidine 294

Clopidogrel 297

Cloprostenol 299

Clorazepate 301

Cloxacillin 303

Cobalamin 304

Codeine 307

Colchicine 309

Corticotropin 311

Cortisone 312

Cosyntropin 314

Crofelemer 316

Cromolyn (Inhaled) 317

Cyclophosphamide 318

Cyclosporine (Systemic) 322

Cyproheptadine 327

Cytarabine 329

Dacarbazine (DTIC) 332

Dactinomycin 334

Dalteparin 335

Danofloxacin 337

Dantrolene 339

Dapsone 341

Darbepoetin Alfa 342

Decoquinate 344

Deferoxamine 346

Deracoxib 347

Desflurane 349

Deslorelin 351

Desmopressin 352

Desoxycorticosterone Pivalate (DOCP) 355

Detomidine 358

Dexamethasone 361

Dexmedetomidine 367

Dexrazoxane 372

Dextran 70 373

Dextromethorphan 375

Dextrose 50% Injection 376

Diazepam 378

Diazoxide 382

Dichlorphenamide 384

Diclazuril 385

Diclofenac, Topical 387

Dicloxacillin 389

Diethylstilbestrol (DES) 390

Digoxin 392

Diltiazem 396

Dimenhydrinate 399

Dimercaprol (BAL) 400

Dimethyl Sulfoxide 402

Diminazene 404

Dinoprost 405

Diphenhydramine 409

Diphenoxylate/Atropine 412

Dipyrone 413

Dobutamine 416

Docusate 418

Dolasetron 419

Domperidone 420

Dopamine 422

Doramectin 424

Doxapram 426

Doxepin 429

Doxorubicin 430

Doxycycline 433

Edetate Calcium Disodium (CaEDTA) 438

Edrophonium 440

Emodepside/Praziquantel 442

Enalapril 445

Enoxaparin 448

Enrofloxacin 450

Ephedrine 455

Epinephrine 457

Epirubicin 460

Epoetin Alfa 463

Eprinomectin/Praziquantel 465

Eprinomectin 467

Epsiprantel 469

Ergocalciferol 470

Ertapenem 472

Erythromycin 473

Esmolol 477

Esomeprazole 478

Estradiol 481

Estriol 483

Ethambutol 485

Ethanol 487

Etodolac 489

Etomidate 491

Euthanasia Agents with Pentobarbital 493

Exenatide 494

Famciclovir 498

Famotidine 499

Fatty Acids, Omega- 3 501

Felbamate 503

Fenbendazole 505

Fenofibrate 508

Fenoldopam 510

Fentanyl, Injection 512

Fentanyl, Transdermal Patch 515

Ferrous Sulfate 519

Fexofenadine 521

Filgrastim (Granulocyte Colony Stimulating Factor; GCSF) 522

Finasteride 524

Firocoxib 525

Florfenicol 528

Fluconazole 530

Flucytosine 534

Fludrocortisone 535

Flumazenil 537

Flumethasone 539

Flunixin 541

Fluorouracil 544

Fluoxetine 547

Fluralaner 549

Fluticasone 552

Fluvoxamine 554

Folic Acid 556

Fomepizole 558

Fosfomycin 559

Frunevetmab 561

Furazolidone 562

Furosemide 563

Gabapentin 568

Gamithromycin 571

Gemcitabine 572

Gemfibrozil 574

Gentamicin, Systemic 576

Glipizide 580

Glucagon 582

Glucosamine/Chondroitin Sulfate 583

Glyburide 585

Glycerin, Oral 587

Glycopyrrolate 588

Gonadorelin 591

Granisetron 593

Grapiprant 594

Griseofulvin 596

Guaifenesin, Intravenous 598

Hemoglobin Glutamer- 200 (Bovine) 601

Heparin 603

Hyaluronate 606

Hydralazine 607

Hydrochlorothiazide 610

Hydrocodone Combinations 612

Hydrocortisone 615

Hydrogen Peroxide 3% (Oral) 618

Hydromorphone 619

Hydroxychloroquine 623

Hydroxyethyl Starch (HES) Colloids 625

Hydroxyurea 628

Hydroxyzine 629

Hyoscyamine 632

Hypertonic Saline (7% to 7.5%) 633

Ifosfamide 635

Imepitoin 637

Imidacloprid, Systemic 639

Imidapril 640

Imidocarb 642

Imipenem/Cilastatin Sodium 644

Imipramine 646

Immune Globulin (Human), Intravenous 649

Insulin, Aspart 651

Insulin, Detemir 655

Insulin, Glargine 658

Insulin, Lente 662

Insulin, Lispro 666

Insulin, NPH 670

Insulin, Protamine Zinc 674

Insulin, Regular (Crystalline Zinc) 677

Interferon Alfa, Human Recombinant 681

Interferon Omega, Feline Origin 683

Iodide (Potassium-, Sodium-) 685

Iohexol 687

Ipratropium 689

Irbesartan 690

Iron Dextran 692

Isoflupredone 693

Isoflurane 695

Isoniazid (INH) 698

Isoproterenol 700

Isotretinoin 701

Isoxsuprine 703

Itraconazole 704

Ivermectin 709

Ivermectin/Clorsulon 714

Kaolin/Pectin 715

Ketamine 717

Ketoconazole, Systemic 725

Ketoprofen 729

Ketorolac 732

L- Theanine 733

Lactulose 735

Lanthanum 736

Leflunomide 738

Leucovorin 740

Leuprolide 741

Levamisole 743

Levetiracetam 746

Levothyroxine 749

Lidocaine, Local Anesthetic 752

Lidocaine (Intravenous; Systemic) 756

Lincomycin 760

Linezolid 762

Liothyronine 764

Lipid Emulsion, Intravenous (ILE) 766

Lisinopril 769

Lokivetmab 771

Lomustine 773

Loperamide 775

Loratadine 777

Lorazepam 778

Losartan 781

Lotilaner 783

Lufenuron/Lufenuron Combination Products 785

Lysine 788

Magnesium Hydroxide 789

Magnesium, IV 791

Mannitol 793

Marbofloxacin 796

Maropitant 799

Mavacoxib 802

Mechlorethamine 804

Meclizine 805

Medetomidine 807

Medetomidine/Vatinoxan 811

Medium Chain Triglycerides; (MCT) Oil 814

Medroxyprogesterone 815

Megestrol 817

Meglumine Antimoniate 819

Melarsomine 821

Melatonin 823

Meloxicam 825

Melphalan 829

Meperidine 831

Mepivacaine 834

Meropenem 837

Metergoline 839

Metformin 840

Methadone 842

Methazolamide 846

Methenamine 848

Methimazole 849

Methionine 852

Methocarbamol 854

Methotrexate 856

Methylene Blue 859

Methylphenidate 861

Methylprednisolone 863

Metoclopramide 867

Metoprolol 870

Metronidazole 873

Metyrapone 877

Mexiletine 878

Midazolam 880

Milbemycin Oxime 885

Miltefosine 887

Mineral Oil 889

Minocycline 890

Mirtazapine 893

Misoprostol 896

Mitotane 899

Mitoxantrone 902

Molybdates 904

Montelukast 905

Morantel 906

Morphine 907

Moxidectin/Moxidectin Combination Products 912

Mycobacterial Cell Wall Fraction Immunomodulator 918

Mycophenolate 920

Nalbuphine 923

Naloxone 924

Naltrexone 926

Neomycin 928

Neostigmine 930

Appendix 1480

Veterinarian’s Guide to Writing Prescriptions 1480

Indication 1516

Pharmacist’s Quick Guide to Veterinary Prescriptions: A Whole Different Animal 1482

Important Contact Information 1483

Drug Store Toxins in Small Animal Species 1484

Overdose and Toxin Exposure Decontamination

Guidelines 1487

Multidrug Sensitivity (MDR1 Mutation) in Dogs and Cats 1488

How to Find a Quality- Assured Compounding Pharmacy 1490

Glucocorticoid Agents, General Information 1491

Insulin, General Information 1494

Opioids, General Information 1498

Penicillins, General Information 1498

Antimicrobials in Human and Veterinary Medicine: A Global Classification 1500

ARCI UCGFS Classifications 1503

Extra-Label Drug Use 1503

Veterinary Feed Directive 1504

Conversion Tables for Weight in Kilograms to Body Surface Area (m²) 1506

Conversion of Conventional Chemistry Units to SI Units 1507

Milliequivalents and Molecular Weights, 1507

Solubility Definitions 1508

Parenteral Fluids 1508

Normal Vital Signs 1510

Reference Laboratory Ranges 1510

Estrus and Gestation Periods: Dogs and Cats 1515

Systemic Drugs Sorted by Therapeutic Class or Major Indication 1516

Index 1522

About the Authors

James A. Budde, PharmD, RPh, DICVP
Dr. Budde is Senior Pharmacy Officer for Plumb’s^® and is based out of Madison, Wisconsin.

Dawn M. McCluskey, DVM
Dr. McCluskey is Veterinary Officer of Pharmacy for Plumb’s^® and is based out of Madison, Wisconsin.

Find drug dosages and other critical information for prescribing drugs to animals quickly and efficiently in this fully updated new edition of this must-have veterinary resource

The Tenth Edition of Plumb’s^® Veterinary Drug Handbook updates the most comprehensive, detailed, and trusted source of drug information relevant to veterinary medicine. Covering dosages, drug interactions, adverse effects, and contraindications, among other key drug details, this bestselling book is a must for practicing veterinarians and anyone requiring reliable information on the use of drugs in animals. Designed for ease of use, the book surveys an exhaustive list of drugs with applications for a wide variety of species, including dogs, cats, birds, small mammals, and farm animals.

This edition includes updates to all 738 drug monographs and adds 30 new monographs, including 9 new insulin monographs, to its exhaustive coverage of drugs used in the care of animals. This new edition:

• Provides an extensively reviewed and updated version of the must-have veterinary drug reference
• Includes 30 new drug monographs, including 9 new insulin monographs
• Updates all 738 drug monographs, with robust citing of new information
• Covers a wide variety of species, including dogs, cats, birds, small mammals, and farm animals
• Presents detailed dosing information for an exhaustive list of drugs used in animals

Plumb’s^® exhaustive coverage of drugs relevant to the veterinary field makes this book an essential reference for veterinarians, veterinary technicians, veterinary pharmacologists, pharmacists with veterinary patients, and libraries that serve these groups.