Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?”

New chapters are shown in bold type. The other chapters will be extensively revised and updated.

INTRODUCTION

1. Approach to Neuromuscular Diagnosis

(The aim of this new chapter is to share the thought process that experienced neuromuscular clinician use in making diagnoses.)

2. Electrodiagnostic Methods for the Study of Nerve and Muscle

BASIC ASPECTS

3. Nerve Physiology

4. Neuromuscular Junction Physiology

5. Muscle Physiology and the Motor Unit

6. Electrodiagnostic Apparatus

7. General Aspects of Needle Electromyography

8. Clinical Aspects of Needle Electromyography

9. Nerve Conduction Studies: Basic Principles and Pathologic Correlations

10. Quantitative and Related Techniques of Electromyography

11. Other Electrodiagnostic Techniques for the Evaluation of Neuromuscular Disorders

12. Electrophysiologic Evaluation of the Autonomic Nervous System

13. Magnetic Resonance Imaging of Nerve and Muscle in Health and Disease

(A brief review of MR technology will be presented. The MR characteristics of healthy muscle and nerve will then be shared. Then, the imaging correlates to various diseases of muscle and nerve will be discussed.)

14. Neuromuscular Ultrasound

(The technology and apparatus will first be introduced. The technique of conducting an evaluation will be presented. The imaging characteristics of normal muscle and nerve will be discussed before moving to a discussion of the correlates to common disease of muscle and nerve.)

CLINICAL ASPECTS

15. Myopathic Disorders and Myalgia

16. Motor Neuron Disorders

17. Muscle Fiber and Motor Unit Hyperactivity States

18. Polyneuropathy and Mononeuropathy Multiplex

19. Root and Plexus Lesions

20. Neuromuscular Junction Disorders

NERVES IN THE UPPER EXTREMITIES

21. Median Neuropathies

22. Ulnar Neuropathies

23. Radial Neuropathies

24. Disturbances of Other Nerves in the Upper Extremities

NERVES IN THE LOWER EXTREMITIES

25. Peroneal Neuropathies

26. Tibial and Sural Neuropathies

27. Sciatic Neuropathies

28. Disturbances of Other Nerves in the Lower Extremities

CRANIAL NERVES

29. Facial Neuropathies

30. Disturbances of Other Cranial Nerves and the Phrenic Nerve

CENTRAL NERVOUS SYSTEM

31. Electrophysiologic Evaluation of Selected Aspects of the Central Nervous System

Appendix:

A Glossary of Terms Used in Clinical Electromyography

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